@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-pasteur-00861805v1> a dcat:Dataset ;
    dct:description """
              Upon antiretroviral therapy (ART) human immunodeficiency virus (HIV)/human T-cell lymphotropic virus type 1 (HTLV-1) co-infected individuals frequently develop neurological disorders through hitherto unknown mechanisms. Here, we show that effective anti-HIV ART increases HTLV-1 proviral load through a polyclonal integration pattern of HTLV-1 in both CD4(+) and CD8(+) T-cell subsets that is reminiscent of that typically associated with HTLV-1-related inflammatory conditions. These data indicate that preventing ART-triggered clonal expansion of HTLV-1-infected cells in co-infected individuals deserves investigation.
            """ ;
    dct:identifier "pasteur-00861805" ;
    dct:issued "2026-05-09T18:13:27.246876"^^xsd:dateTime ;
    dct:language "en" ;
    dct:modified "2026-05-09T18:13:27.246882"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Antiretroviral therapy promotes an inflammatory-like pattern of human T-cell lymphotropic virus type 1 (HTLV-1) replication in human immunodeficiency virus type 1/HTLV-1 co-infected individuals." ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
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    dcat:keyword "infoeu-reposemanticsarticle",
        "journal-articles",
        "mesh-anti-retroviral-agents",
        "mesh-antiretroviral-therapy-highly-active",
        "mesh-cd4-positive-t-lymphocytes",
        "mesh-cd8-positive-t-lymphocytes",
        "mesh-coinfection",
        "mesh-hiv-infections",
        "mesh-htlv-i-infections",
        "mesh-human-t-lymphotropic-virus-1",
        "mesh-humans",
        "mesh-proviruses",
        "mesh-viral-load",
        "mesh-virus-integration",
        "mesh-virus-replication",
        "sdvcanlife-sciences-q-biocancer",
        "sdvlife-sciences-q-bio",
        "sdvmpvirlife-sciences-q-biomicrobiology-and-parasitologyvirology" ;
    dcat:landingPage <ISSN:%200022-1317> .

<ISSN:%200022-1317> a foaf:Document .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-pasteur-00861805v1/resource/e9eab21d-2c9a-4e8f-bf04-cb1b8d35779a> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-09T18:13:27.255344"^^xsd:dateTime ;
    dct:modified "2026-05-09T18:13:27.231757"^^xsd:dateTime ;
    dct:title "Antiretroviral therapy promotes an inflammatory-like pattern of human T-cell lymphotropic virus type 1 (HTLV-1) replication in human immunodeficiency virus type 1/HTLV-1 co-infected individuals." ;
    dcat:accessURL <https://riip.hal.science/pasteur-00861805> .

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