@prefix dcat: . @prefix dct: . @prefix foaf: . @prefix vcard: . @prefix xsd: . a dcat:Dataset ; dct:description """ BACKGROUND: In many Asian countries, Klebsiella pneumoniae (KP) is the second pathogen responsible for community-acquired pneumonia. Yet, very little is known about KP etiology in ALRI in Cambodia, a country that has one of the weakest medical infrastructures in the region. We present here the first clinico-radiological description of KP community-acquired ALRI in hospitalized Cambodian patients. METHODS: Through ALRI surveillance in two provincial hospitals, KP was isolated from sputum and blood cultures, and identified by API20E gallery from patients ≥ 5 years-old with fever and respiratory symptoms onset ≤14 days. Antibiotics susceptibility testing was provided systematically to clinicians when bacteria were isolated. We collected patients' clinical, radiological and microbiological data and their outcome 3 months after discharge. We also compared KP-related with other bacteria-related ALRI to determine risk factors for KP infection. RESULTS: From April 2007 to December 2009, 2315 ALRI patients ≥ 5 years-old were enrolled including 587 whose bacterial etiology could be assigned. Of these, 47 (8.0%) had KP infection; their median age was 55 years and 68.1% were females. Reported prior medication was high (42.5%). Patients' chest radiographs showed pneumonia (61.3% including 39% that were necrotizing), preexisting parenchyma lesions (29.5%) and pleural effusions alone (4.5%) and normal parenchyma (4.5%). Five patients had severe conditions on admission and one patient died during hospitalization. Of the 39 patients that were hospital discharged, 14 died including 12 within 1 month after discharge. Only 13 patients (28%) received an appropriate antibiotherapy. Extended-spectrum beta-lactamases (ESBL) - producing strains were found in 8 (17.0%) patients. Female gender (Odds ratio (OR) 2.1; p = 0.04) and diabetes mellitus (OR 3.1; p = 0.03) were independent risk factors for KP-related ALRI. CONCLUSIONS: KP ALRI in Cambodia has high fatality rate, are more frequently found in women, and should be considered in diabetic patients. The extremely high frequency of ESBL-producing strains in the study is alarming in the context of uncontrolled antibiotic consumption and in absence of microbiology capacity in most public-sector hospitals. """ ; dct:identifier "pasteur-00853147" ; dct:issued "2026-05-10T01:22:54.193400"^^xsd:dateTime ; dct:language "en" ; dct:modified "2026-05-10T01:22:54.193404"^^xsd:dateTime ; dct:publisher ; dct:title "Klebsiella pneumoniae related community-acquired acute lower respiratory infections in Cambodia: clinical characteristics and treatment." ; dcat:contactPoint [ a vcard:Organization ; vcard:fn "CCSD" ] ; dcat:distribution ; dcat:keyword "community-acquired", "diabetes-mellitus", "extended-spectrum-betalactamases", "infoeu-reposemanticsarticle", "journal-articles", "klebsiella-pneumoniae", "mesh-adult", "mesh-aged", "mesh-anti-bacterial-agents", "mesh-beta-lactamases", "mesh-blood", "mesh-bronchopneumonia", "mesh-cambodia", "mesh-community-acquired-infections", "mesh-female", "mesh-humans", "mesh-klebsiella-infections", "mesh-klebsiella-pneumoniae", "mesh-male", "mesh-microbial-sensitivity-tests", "mesh-middle-aged", "mesh-risk-factors", "mesh-sputum", "mesh-survival-analysis", "pneumonia", "sdvmpvirlife-sciences-q-biomicrobiology-and-parasitologyvirology" ; dcat:landingPage . a foaf:Document . a dcat:Distribution ; dct:format "HTML" ; dct:issued "2026-05-10T01:22:54.195710"^^xsd:dateTime ; dct:modified "2026-05-10T01:22:54.164160"^^xsd:dateTime ; dct:title "Klebsiella pneumoniae related community-acquired acute lower respiratory infections in Cambodia: clinical characteristics and treatment." ; dcat:accessURL . a foaf:Agent ; foaf:name "test_moissonnage_selune" .