@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-hal-00964249v1> a dcat:Dataset ;
    dct:description """
              Background: Adults suffering from wheat-dependant, exercise-induced anaphylaxis (WDEIA) develop IgE directed against wheat ω5-gliadins (major allergens for this allergy) and against wheat low-molecular weight glutenin subunits (LMW-GS). However, the ability of LMW-GS to trigger an inflammatory response is still unknown. It also remains to be determined if IgE from these patients bind the same epitopes on LMW-GS and ω5-gliadins or if the epitopes are independent. Methods: WDEIA patients were selected and skin prick tests (SPTs) were performed on them using commercial gluten, wheat flour extracts, prolamin fractions and a purified natural LMW-GS P42. The IgE-binding ability of natural and recombinant wheat prolamins was verified by immunoblot experiments. Cross-reactivity between LMW-GS and ω5-gliadins was studied by immunoblot inhibition experiments, using purified natural ω5-gliadin as an inhibitor. Results: Patients developed positive SPTs with natural LMW-GS fractions and/or with the purified LMW-GS P42. Natural and recombinant LMW-GS were highly reactive with patient IgE in immunoblot experiments, as was ω5-gliadin. However, differences in reactivity were evident within the LMW-GS group. Except for one recombinant LMW-GS (P73), IgE cross-reactivity between LMW-GS and natural ω5-gliadin was only partial. Conclusion: LMW-GS are able to promote local inflammation and they share common epitopes with ω5-gliadins. The nature of these epitopes is discussed. LMW-GS also carried specific epitopes, completely independent from the ω5-gliadin epitopes. Thus, LMW-GS behaved partly as independent allergens.
            """ ;
    dct:identifier "hal-00964249" ;
    dct:issued "2026-05-05T21:43:38.863000"^^xsd:dateTime ;
    dct:language "en" ;
    dct:modified "2026-05-05T21:43:38.863004"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Low Molecular Weight Glutenins in Wheat-Dependant, Exercise-Induced Anaphylaxis: Allergenicity and Antigenic Relationships with Omega 5-Gliadins" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
    dcat:distribution <https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-hal-00964249v1/resource/263942bd-42fe-4dba-9a8e-298154c28cf3> ;
    dcat:keyword "5-gliadins",
        "exercise-induced-anaphylaxis",
        "ige-binding",
        "immunoblot-inhibition-method",
        "infoeu-reposemanticsarticle",
        "journal-articles",
        "low-molecular-weight-glutenins",
        "recombinant-proteins",
        "sdvsalife-sciences-q-bioagricultural-sciences",
        "skin-prick-test",
        "wheat-allergy",
        "wheat-dependant" ;
    dcat:landingPage <ISSN:%201018-2438> .

<ISSN:%201018-2438> a foaf:Document .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-hal-00964249v1/resource/263942bd-42fe-4dba-9a8e-298154c28cf3> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-05T21:43:38.896214"^^xsd:dateTime ;
    dct:modified "2026-05-05T21:43:38.848525"^^xsd:dateTime ;
    dct:title "Low Molecular Weight Glutenins in Wheat-Dependant, Exercise-Induced Anaphylaxis: Allergenicity and Antigenic Relationships with Omega 5-Gliadins" ;
    dcat:accessURL <https://hal.science/hal-00964249> .

<https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> a foaf:Agent ;
    foaf:name "test_moissonnage_selune" .