Tissue morphogenesis is a key point remaining weakly understood in development biology. In particular, whatever the species considered (animals and vegetables), most of formed epithelial tissues show analogous cell polygonal distributions (Gibson 2009). Accordingly, one may wonder if there are invariant features governing this process. Among the numerous studies performed up today to answer this question, only few approaches including physical models have been developed (Graner et Glazier, 1993; Martinand-Mari et al., 2009). These models allow cellular reorganisation within tissues already formed but by considering only limited movements and without any growing cells, which does not exactly correspond to biological tissue morphogenesis.
Divided media based simulations of tissue morphogenesis