Sacculo-collic pathway dysfunction accompanying auditory neuropathy
type: Distribution
access URL: https://hal.science/hal-00090313
format: HTML
issued: 2026-05-08T06:58:21.639850
modified: 2026-05-08T06:58:21.626457

test_moissonnage_selune
type: Agent

Sacculo-collic pathway dysfunction accompanying auditory neuropathy
type: Dataset
contact point: Organization
  fn: CCSD
keyword: saculo-collic
keyword: infoeu-reposemanticsarticle
keyword: auditory-neuropathy
keyword: hearing
keyword: journal-articles
keyword: sdvmheplife-sciences-q-biohuman-health-and-pathology
landing page: 0001-6489
description: CONCLUSIONS: In a patient with bilateral auditory neuropathy (AN), the vestibular-evoked myogenic potential (VEMP) was probably absent because of a neuropathy involving the inferior vestibular nerve and/or its end organ, the saccule. Our result can therefore be interpreted as a concomitant unilateral sacculo-collic neuropathy. We suggest the use of more precise terms to characterize AN patients with involvement of different parts of the inner ear and its innervations. We encourage detailed vestibular assessment in patients with AN in order to assess the co-existence of any symptomatic or asymptomatic vestibular disorder. Information such as that provided in this report will be valuable for clinicians caring for this group of patients. OBJECTIVE: AN is a disorder characterized by the absence or severe impairment of auditory brainstem responses in the presence of normal cochlear outer hair cell function as revealed by otoacoustic emissions (OAEs) and/or electrocochleography (ECoG). A variety of processes and etiologies are thought to be involved in its pathophysiology. In most literature reports the auditory profile of patients with AN is discussed. However, the extent of vestibular involvement, especially that involving the saccule, is not known. We performed vestibular tests to assess the status of the saccule in a patient with AN. MATERIAL AND METHODS: One patient with AN was studied. The patient was a right-handed 21-year-old female with chief complaints of hearing loss and speech perception difficulty. RESULTS: The auditory test results were consistent with the diagnosis of AN, i.e. absent auditory brainstem responses, moderate hearing loss, an inappropriately profound speech discrimination score and the presence of OAEs and measurable cochlear microphonics on ECoG. On neurological examination, gait and balance tests were normal. Ice-water caloric testing induced a sensation of dizziness in both ears. Short tone-burst VEMPs showed no response on left-ear stimulat…
issued: 2026-05-08T06:58:21.634366
language: en
modified: 2026-05-08T06:58:21.634370