@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

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              Two collections of oligonucleotides have been designed for preparing pangenomic human and mouse microarrays. A total of 148,993 and 121,703 oligonucleotides were designed against human and mouse transcripts. Quality scores were created in order to select 25,342 human and 24,109 mouse oligonucleotides. They correspond to: (i) a BLAST-specificity score; (ii) the number of expressed sequence tags matching each probe; (iii) the distance to the 3' end of the target mRNA. Scores were also used to compare in silico the two microarrays with commercial microarrays. The sets described here, called RNG/MRC collections, appear at least as specific and sensitive as those from the commercial platforms. The RNG/MRC collections have now been used by an Anglo-French consortium to distribute more than 3500 microarrays to the academic community. Ad hoc identification of tissue-specific transcripts and a approximately 80% correlation with hybridizations performed on Affymetrix GeneChiptrade mark suggest that the RNG/MRC microarrays perform well. This work provides a comprehensive open resource for investigators working on human and mouse transcriptomes, as well as a generic method to generate new microarray collections in other organisms. All information related to these probes, as well as additional information about commercial microarrays have been stored in a freely-accessible database called MEDIANTE.
            """ ;
    dct:identifier "hal-00088266" ;
    dct:issued "2026-05-09T01:31:46.419773"^^xsd:dateTime ;
    dct:language "en" ;
    dct:modified "2026-05-09T01:31:46.419777"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes." ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
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        "mesh-animals",
        "mesh-databases-nucleic-acid",
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        "mesh-gene-expression-profiling",
        "mesh-humans",
        "mesh-internet",
        "mesh-mice",
        "mesh-oligonucleotide-array-sequence-analysis",
        "mesh-oligonucleotide-probes",
        "mesh-transcription-genetic",
        "sdvgenlife-sciences-q-biogenetics" ;
    dcat:landingPage <ISSN:%200305-1048> .

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    dct:issued "2026-05-09T01:31:46.421965"^^xsd:dateTime ;
    dct:modified "2026-05-09T01:31:46.396925"^^xsd:dateTime ;
    dct:title "An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes." ;
    dcat:accessURL <https://hal.science/hal-00088266> .

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