The concerted modulation of proliferation and migration contributes to the specification of the cytoarchitecture and dimensions of cortical areas
type: Dataset
description: Regionalization of cell-cycle kinetics of cortical precursors has been described in non-human primates and rodents indicating a fate map of areal distinct proliferative programs in the germinal zones of the neocortex. It remains to be understood how proliferative gradients during corticogenesis are transcribed into a stepwise function to form adult areal borders. Here we have used the monkey areas17 and 18, which show striking cytoarchitectonic differences as a model system for studying how developmental events establish areal boundaries in the adult. We present data indicating that the events that are involved in the formation of a sharp border separating two areas involve an orchestration of diverse phenomena including differential rates of proliferation, migration and tangential expansion.
issued: 2026-05-15T06:58:53.561540
language: en
modified: 2026-05-15T06:58:53.561546
contact point: Organization
  fn: CCSD
keyword: cortical-plate
keyword: infoeu-reposemanticsarticle
keyword: journal-articles
keyword: neocortex
keyword: primate
keyword: sdvneulife-sciences-q-bioneurons-and-cognition-q-bionc
keyword: subventricular-zone
landing page: 1047-3211

The concerted modulation of proliferation and migration contributes to the specification of the cytoarchitecture and dimensions of cortical areas
type: Distribution
format: HTML
issued: 2026-05-15T06:58:53.583657
modified: 2026-05-15T06:58:53.540462
access URL: https://hal.science/hal-00077632

test_moissonnage_selune
type: Agent