Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid
type: Dataset
description: 12 pages
landing page: Archives of biochemistry and biophysics.
keyword: -interactions
keyword: active-site-topology
keyword: difference-visible-spectroscopy
keyword: drug-metabolism
keyword: hydroxylation
keyword: infoeu-reposemanticsarticle
keyword: journal-articles
keyword: sdvbbmlife-sciences-q-biobiochemistry-molecular-biology
keyword: sdvtoxlife-sciences-q-biotoxicology
keyword: site-directed-mutagenesis
keyword: yeast-expressed-cyp-2cs
issued: 2026-05-19T08:34:53.812588
modified: 2026-05-19T08:34:53.812595
language: en
contact point: Organization
  fn: CCSD

test_moissonnage_selune
type: Agent

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid
type: Distribution
format: HTML
access URL: https://hal.science/hal-00069626
issued: 2026-05-19T08:34:53.887926
modified: 2026-05-19T08:34:53.782384