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BCG immunotherapy for bladder cancer : characterization and modeling of the b...
Intravesical instillation of bacillus Calmette-Guérin (BCG) for non-muscle invasive bladder cancer is one of the few examples of successful immunotherapy in the... -
Cyclic Nucleotide Phosphodiesterases (PDEs) in Smooth Muscle : Expression, Fu...
The aim of the present thesis was to characterize the role of the different families of phosphodiesterases (PDEs), the enzymes degrading 3'-5'-cyclic adenosine... -
Predictive models of toxicity in intensity modulated radiotherapy
This thesis is focused on the predictive models of irradiation induced toxicities in intensity modulated radiotherapy. Six different NTCP models were implemented and... -
Health effects of exposure to disinfection by-products
Background. Chlorine is the most widely used disinfectant for drinking water treatment. During treatment process, the natural organic matter present in water reacts... -
Characterization of molecular transport through the bladder : clinical and ph...
Bladder diseases are numerous and mostly require medication. Drugs can be administered by intravesical route, thereby increasing efficiency and reducing systemic side...
