-
Molecular mechanisms of plant response to ionising radiation. Exploration of ...
Terrestrial organisms are exposed to low doses of ionising radiation from natural or anthropogenic sources. The major effects of the radiations are due to DNA... -
A chemical biology approach for the discovery of molecules acting on tumour i...
Since the emergence of the concept of cancer stem cells (CSC), such cells were isolated from various solid tumors including glioblastomas. The CSC and the properties... -
Impact of the earthworm Aporrectodea caliginosa on plant growth, development ...
Plants develop and evolve in interaction with soil organisms. The impact of earthworms, likely positive, has been attributed to modifications of physical, chemical or... -
Search for genes involved in the sexual development of the fungus Podospora a...
The filamentous fungus, Podospora anserina, has two mating-type idiomorphs, mat+ and mat-. The mat+ sequence contains one gene FPR1, while mat- contains three genes:... -
Major Histocompatibility Complex and functional genomics in spondyloarthritis
Spondyloarthritis (SpA) is a frequent chronic inflammatory rheumatic disorder, with a prevalence of 0.3% in France. Pathological mechanisms leading to SpA remain... -
Molecular mechanisms implicated in bone resorption
Bone remodeling is a physiological process by which old bone is replaced by new bone. Osteoclasts are multinucleated giant cells of the monocytic lineage. Their... -
Molecular comparison of orthodox Medicago truncatula seeds and recalcitrant C...
Desiccation tolerance (DT) is defined as the ability to survive in the dry state and resume metabolic activity upon imbibition. Unlike orthodox seeds, that acquire DT... -
Post-genomic analyses : study of IL-33 and BIN1 involvement in Alzheimer's di...
Genomic analyses allowed to identify genes and proteins involved inAlzheimer’s Disease (AD). In the laboratory, genetic and transcriptomic approachesrevealed two genes...
