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Induction of gene expression by small RNAs in mammalian cells
In the majority of the eucaryote, the presence of double-strands RNA induce the inhibition of gene expression base on the complementary of sequence. The best known... -
Identification of Dermcidin as a novel binding protein of Nck1 and characteri...
International audience -
Modifications of lipidic nanocapsules by post-formulation processes. Creation...
This work established the identity card of nanoparticles developped in our laboratory; these nanoparticles are called lipidic nanocapsules. Indeed, these lipidic... -
Suppression of multidrug resistance by treatment with TRAIL in human ovarian ...
International audience -
New targeted approaches for the treatment of Ewing's sarcoma family of tumors
This work has enabled a comprehensive evaluation of different sequences of siRNAs directed against EWS/Fli-1 in the treatment of tumors of the Ewing sarcoma family of... -
Kinetic analysis of RNA interference in nuclear and cytoplasmic compartments ...
RNA interference (RNAi) is a mechanism by which double stranded RNA trigger the sequence specific degradation of RNA. In mammalian cells, RNAi can be induced by short... -
Biofunctional micellar nanoparticles from peptide-b-polymer chimeras
International audience -
Involvement of Cx43 in the hypothalamic glucose-sensing
Résumé publié dans les revues associées au congrès de la SFD à Nice et de P2T à Dijon ; tItre original : Implication de la Cx43 dans le glucose-sensing hypothalamique -
Design of double-walled carbon nanotubes for biomedical applications
International audience -
Development of nanocarriers for systemic nucleic acid administration
Two different types of nanocarriers, lipid nanocapsules (LNC) and multimodular systems (MMS) were developed for systemic administration of two types of nucleic acids,... -
Development of novel nanovehicles for anti-HCV/HCC therapies
This work concerns the development of a nanoparticle vector system for RNA interference,constituting a new therapeutic option applicable to viral and tumor...
