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Alteration of TEAD1 expression levels confers apoptotic resistance through th...
International audience -
Role of RNA interference and Mmi1 in the regulation of sexual differentiation...
RNA interference (RNAi) is a cellular process known for inhibiting gene expression in a sequence-specific manner. In the fission yeast Schizosaccharomyces pombe, this... -
Study of the antioxydant capacity in link with reproduction in the Pacific oy...
The “cost of reproduction” is a concept defining that a high reproductive investment has a price that is paid later by an acceleration of senescence. That may... -
New targeted approaches for the treatment of Ewing's sarcoma family of tumors
This work has enabled a comprehensive evaluation of different sequences of siRNAs directed against EWS/Fli-1 in the treatment of tumors of the Ewing sarcoma family of... -
Kinetic analysis of RNA interference in nuclear and cytoplasmic compartments ...
RNA interference (RNAi) is a mechanism by which double stranded RNA trigger the sequence specific degradation of RNA. In mammalian cells, RNAi can be induced by short... -
Efficient gene expression from integration-deficient lentiviral vectors in th...
International audience -
Functional analysis of TaGW2, an E3 ligase of the RING type, in the developme...
Wheat, Triticum aestivum, is one of the world’s major cereal crops and is of considerable importance to human nutrition, supplying one-fifth of the calories consumed... -
Adenovirus mediated RNA interference as new therapeutic tool against cervical...
Cervical cancer is the third most common female cancer. Infection by human papillomavirus (mainly HPV-16 and 18), with tropisms for mucosal or cutaneous squamous... -
MicroRNA involvement in mammary gland development and breast cancer
International audience -
Induction of transient macroapertures in endothelial cells through RhoA inhib...
The GTPase RhoA is a major regulator of the assembly of actin stress fibers and the contractility of the actomyosin cytoskeleton. The epidermal cell differentiation... -
Attenuated Salmonella choleraesuis-mediated RNAi targeted to conserved region...
International audience -
Development of a new cell-on-chip format for high-content phenotyping
Nowadays biology research is faced with a considerable amount of genomic data which has to be functionally characterised in order to bring new concepts, which will... -
Down-regulation of the TaGW2 gene by RNA interference results in decreased gr...
For important food crops such as wheat and rice, grain yield depends on grain number and size. In rice (Oryza sativa), GW2 was isolated from a major quantitative trait... -
The role of RNA interference in the developmental separation of blood and lym...
International audience -
Development of cationic oligonucleotides for molecular hybridization and therapy
Oligonucleotides are finding an extremely large number of applications in molecular diagnostics and might become a very selective class of drugs for the treatment of a...
