58 datasets found

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Endocannabinoids form a novel class of intercellular messengers, the functions of which include retrograde signaling in the brain and mediation or modulation of...

Inhaled nitric oxide (iNO) is one of the most promising therapies used in neonates, but littlei known about its effect on the developing brain. We explored the effects...

Dihydroceramide ?4-desaturase 1 (DES1) catalyzes the last step of the de novo ceramide biosynthesis, which consists of the introduction of a trans ?4-double bond in...

To determine whether members of the Netrin-1 and Slit families and their receptors are expressed after central nervous system (CNS) injury, we performed in situ...

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The main objective of this thesis was to investigate the role of the ventral hippocampus (HPC) and the reuniens (Re) and rhomboid (Rh) thalamic nuclei in the cognitive...

Les douleurs neuropathiques sont associées dans la moelle épinière à des altérations neuronales et gliales. Ces cellules libèrent des médiateurs inflammatoires comme...

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C.E.G and P.B. contributed equally to this work.

We have used a model of postlesional reinnervation to observe the interactions between synaptic partners during neosynaptogenesis to determine how the developmental...

211 pages

In the present work, our aim was the implementation of proton NMR spectroscopy methods optimized for glutamate detection and their application to Parkinson's disease,...

Voltage-gated sodium channels, or Nav channels, play a key role in neuronal excitability and in the emission and propagation of action potentials. Among the different...

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Short early manipulations of rodent postnatal environment may trigger long-term effects on neurobiological and behavioural phenotypes in adulthood. However, little is...