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Huntingtin and mitosis
Huntington disease (HD) is an autosomal-dominant neurodegenerative disorder caused by the pathogenic expansion of the poly-glutamine (polyQ) N-terminal stretch in the... -
Implications of post-transcriptional modifications in the regulation of MITF ...
The Microphthalmia associated transcription factor MITF and the Mitotic Activated Protein Kinase signaling pathway (MAPK) are crucial elements for the differentiation,... -
The diversity and evolution of cell cycle regulation in alpha-proteobacteria:...
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Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestina...
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TRAIL signalling regulation by ezrin
Background and Aim: TRAIL has sparked a growing interest in oncology due to its ability to selectively trigger cancer cell death while sparing normal cells. The... -
Regulation of the NADPH oxidase NOX1 : a crucial role of NOXA1 (NOX Activator...
The NOX family of NADPH oxidases are enzymes which function is dedicated to the production of reactive oxygen species. NOX1, a member of this family is expressed... -
Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resist...
Published on behalf of the European Society of Cardiology -
A conserved phosphorylation site regulates the transcriptional function of ET...
International audience -
Regulation of ERK by cannabinoids in hippocampes.
Endocannabinoids form a novel class of intercellular messengers, the functions of which include retrograde signaling in the brain and mediation or modulation of... -
Role of Eg5 regulation and motor properties in bipolar spindle assembly in Xe...
In this study, we show that Eg2 phosphorylation of Eg5 is not important for its function in bipolar spindle formation in Xenopus egg extract. Conversely, Eg5 needs to... -
Improvement of the oxidative stability of nanodiamonds by surface phosphoryla...
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VE-cadherin post-translational modifications : from molecular mechanisms to c...
The vascular endothelium barrier function is influenced by vascular endothelial cadherin (VE-cadherin) modifications such as its cytoplasmic tail tyrosine... -
Dynamic instability of the intracellular pressure drives bleb-based motility
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Optineurin, a new regulator of mitosis
Optineurin ("Optic neuropathy-inducing", Optn) is a protein ubiquitously expressed in vertebrates. This protein is involved in several cellular physiological processes... -
Role of the GGDEF/EAL proteins of L. pneumophila
Legionella pneumophila is an intracellular pathogen found in aquatic environments where it replicates in protozoan hosts. My objectives were to identify molecular... -
Development of a phosphopeptide preconcentration method using monolith in mic...
Protein phosphorylation is a key regulator of cellular signaling pathways. It is involved in most cellular events and strictly controls biological processes such as... -
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.
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Paradoxical Potentiation of Neuronal T-Type Ca2+ Current by ATP at Resting Me...
Despite the marked influence on neuronal physiology of the low-voltage activated T-type Ca(2+) currents, little is known about the intracellular pathways and... -
Identification of pVHL as a novel substrate for Aurora-A in clear cell renal ...
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Unliganded estrogen receptor alpha promotes PC12 survival during serum starva...
International audience
