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Pharmacokinetic and pharmacodynamic variability of fluindione in octogenarians.
International audience -
Heparin bridging therapy and bleeding events in octogenarian inpatients with ...
International audience -
Mathematical modeling of pulmonary tuberculosis therapy: insights from a prot...
International audience -
A control systems approach to HIV prevention with impulsive control input
International audience -
Pharmacokinetic pharmacodynamic modeling and simulation methods applied to ev...
Are Evidence-Based Medicine and its associated search for standardization compatible with the patient intra- and interindividual variability in therapeutic response?... -
Development of mechanistic models and evaluation of parameter uncertainty via...
Angiogenesis, the development of new blood vessels from pre-existing vasculator, plays a crucial role in the growth of malignant tumors and the development of... -
A delay differential equation solver for MONOLIX & MLXPLORE
We describe the implementation of a Delay differential Equation (DDE) solver in Monolix, a platform for population modeling of longitudinal data, and MlxPlore, a tool... -
Pharmacokinetics and pharmacodynamic modelling of epinephrine and norepinephr...
The effects of catecholamines are difficult to predict. The between-subject variability observed in clinical setting is multifactorial including constitutional and... -
Extension of the isobolographic approach to interactions studies between more...
International audience -
From dose to clinical effect : use of modeling through drug development to pr...
Epidemiological data demonstrate an inverse correlation between HDL-cholesterol (HDL-C) levels and cardiovascular risk. Therefore, drugs as cholesteryl ester transfer...
