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Interests and limits of bone marrow analysis in forensic toxicology : contrib...
The aim of this work was to evaluate the interest of bone marrow (BM) analysis in forensic toxicology, as an alternative matrix to blood. An analytical method was... -
Predicting in vivo gene expression in macrophages after exposure to benzo(a)p...
International audience -
Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxi...
International audience -
Development of good modelling practice for physiologically based pharmacokine...
International audience -
Assessing the reliability of PBPK models using data from methyl chloride-expo...
International audience -
Physiologically-based kinetic modelling (PBK modelling) : meeting the 3Rs agenda
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Utilisation de modèles mécanistiques de cinétique et d'effets pour l'évaluati...
This dataset has no description
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Linking fate model in freshwater and PBPK model to assess human internal dosi...
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Developing links between systems biology and PBPK modelling
This dataset has no description
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Systems biology PBPK modelling of metabolic interactions
This dataset has no description
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Modélisation en toxicocinétique
This dataset has no description
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Calibration of PBPK models based on in vivo and in vitro data to describe com...
This dataset has no description
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Multi-scale modelling in toxicology : how to bridge the gaps between scales ?
The physiological functions of an organism coexist across several temporal and spatial orders of magnitude. Therefore, the toxic effects of a substance should be... -
Reconstruction of the dynamic exposure to PCBs for Italian population using p...
Polychlorinated biphenyls (PCBs) are persistent contaminants suspected to cause adverse health effects in humans. Due to their extensive use in the past and... -
Integrated modelling of endocrine disruption in zebrafish at different biolog...
Certain chemicals possess the ability of modulating the endocrine systems, associated with reproductive and developmental dysfunctions and abnormal levels of... -
How to integrate in vitro PK/PD information for toxicity prediction
Predicting drugs' in vivo effects from in vitro testing requires modelling processes that are not reproduced by in vitro systems. The most obvious difference between... -
Stochasticity in Physiologically Based Kinetics Models : implications for can...
International audience -
Development of a physiologically based kinetic model for 99m-Technetium-label...
International audience
