-
Poly(Adp-Ribose) Polymerase Signaling Of Topoisomerase 1-Dependent Dna Damage...
International audience -
Transcriptional signature of human macrophages exposed to the environmental c...
International audience -
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymph...
International audience -
Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling p...
International audience -
The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.
International audience -
Ovarian and tubal dysplasia : an early event in the pathogenesis of epithelia...
Background: Histopathological examination of material from prophylactic salpingooophorectomies(pBSO) performed in patients at genetic risk has revealed... -
Parkin: much more than a simple ubiquitin ligase.
International audience -
α-Secretase-derived fragment of cellular prion, N1, protects against monomeri...
International audience -
Cellular prion and its catabolites in the brain: production and function.
International audience -
α-Secretase-derived cleavage of cellular prion yields biologically active cat...
International audience -
p53, a pivotal effector of a functional cross-talk linking presenilins and Pe...
International audience -
A spatial physiological model for p53 intracellular dynamics
In this paper we design and analyse a physiologically based model representing the accumulation of protein p53 in the nucleus after triggering of ATM by DNA damage.... -
ING2 controls the G1 to S-phase transition by regulating p21 expression.
International audience -
MODELLING NUCLEOCYTOPLASMIC TRANSPORT WITH APPLICATION TO THE INTRACELLULAR D...
In this thesis, I discuss two main subjects coming from biology and I propose two models that mimic the behaviours of the biological networks studied. The first part... -
A dp53-JNK-dependant feedback amplification loop is essential for the apoptot...
International audience -
Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust parti...
International audience -
Diverse p63 and p73 isoforms regulate D133p53 expression through modulation o...
International audience -
Role of p53 pathway in the response of soft tissue sarcomas to TNF-alpha trea...
Introduction: Although named for its antitumor properties, TNF-a is implicatedin a wide spectrum of diseases including chronic inflammation, autoimmunity andcancer. It... -
P53 inactivation leads to impaired motor synchronization in mice.
We have combined genetic and pharmacological approaches to investigate the behavioural consequences of inactivation of the murine p53 protein. Our behavioural analysis... -
Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response...
International audience
