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TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch ...
Increasing evidence suggests a critical implication of membrane-associated protease activities in numerous biological processes. ADAM (A Disintegrin and... -
Identification of new regulators of Notch ligand trafficking and signaling ac...
La voie de signalisation Notch est une voie de signalisation conservée et primordiale aussi bien pour le développement des métazoaires que la maintenance de leurs... -
Epithelial to mesenchymal transition-The roles of cell morphology, labile adh...
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Delta-like 4 inhibits choroidal neovascularization despite opposing effects o...
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Ikaros deficiency : from T -ALL to auto-immune disease
The Ikaros transcription factor is a critical regulator of lymphopoeisis. Ikaros is needed for the differentiation of B cell and plays an important role in tumor... -
Role of the post-transcriptional regulators Pumilio1 and Pumilio2 in murine h...
The central properties of stem cells are the pluripotency and the capacity of self-renewal. Hematopoietic stem cells (HSCs) posses such common features that allows... -
ADAM10 metalloprotease regulation by tetraspanins
ADAMs are a sub-family of enzymes called “metalloproteases” which are implicated in a variety of physiological as well as pathological processes through their ability... -
Crystal structure, biochemical and biophysical characterisation of NHR1 domai...
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Novel genes upregulated when NOTCH signalling is disrupted during hypothalami...
International audience
