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Cell number in the Inferior Olive of nervous and leaner mutant mice.
Naturally occurring cell death is an important feature of neuronal network development: the absence of adequate postsynaptic target neurons during a critical period... -
CEREBELLAR PURKINJE CELL LOSS IN HETEROZYGOUS RORA+/-MICE: A LONGITUDINAL STUDY
The staggerer (sg/sg) mutation is a spontaneous deletion in the Rora gene that prevents the translation of the ligand-binding domain (LBD), leading to the loss of RORα... -
C-jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced...
Understanding the regulation of the apoptotic program in neurons by intracellular pathways is currently a subject of great interest. Recent results suggest that c-Jun... -
JNK/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis
Understanding the regulation of the apoptotic program in neurons by intracellular pathways is currently a subject of great interest. Recent results suggest that c-Jun... -
Paradoxical increase of tyroxine hydroxylase-immunoreactive retinopetal fiber...
Weaver mice undergo apoptosis of the granule cell precursors of the cerebellum and nonapoptotic death of mesencephalic dopaminergic cells during post-natal... -
Bcl-2 protection of axotomized Purkinje cells in organotypic culture is age d...
This dataset has no description
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Apoptosis: a target for neuroprotection.
Accumulating evidence strongly suggests that apoptosis contributes to neuronal death in a variety of neurodegenerative contexts. Activation of the cysteine protease... -
Survival of interneurons and parallel fiber synapses in a cerebellar cortex d...
International audience -
Expanded huntingtin activates the c-Jun terminal kinase/c-Jun pathway prior t...
Huntington's disease (HD) is an autosomal neurodegenerative disorder, caused by expansion of a glutamine repeat in the Huntingtin protein. Pathogenesis in HD includes...
