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Distinct pharmacological properties of morphine metabolites at G-protein and ...
International audience -
Evaluation of different size-descriptors in obese subjects using population p...
Pharmacokinetic of drugs may be altered by pathophysiological changes associated with obesity: renal function, body compartments, expression of metabolism proteins.... -
Brief early handling increases morphine dependence in adult rats.
Short early manipulations of rodent postnatal environment may trigger long-term effects on neurobiological and behavioural phenotypes in adulthood. However, little is... -
Calibrated forceps: a sensitive and reliable tool for pain and analgesia studies
Devices designed for mechanical pain threshold studies are often difficult to implement. The purpose of this study was to investigate a simple tool based on calibrated... -
Pharmacology of morphine in obese subjects before and after obesity surgery
In this thesis, we show that obesity is a factor of pharmacodynamic and pharmacokinetic morphine variability. In particular, absorption and exposure to oral morphine... -
Alpha 7 and beta 2*nicotinic receptors control monoamine-mediated locomotor r...
International audience
