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Linking the DNA strand asymmetry to the spatio-temporal replication program :...
Two key cellular processes, namely transcription and replication, require the opening of the DNA double helix and act differently on the two DNA strands, generating... -
In vivo evolution of a beta-lactamase like activity throughout idiotypic pathway
An abzyme (9G4H9) displaying a -lactamase activity was obtained through the idiotypic pathway and has been previously described. Analysis of the catalytic mechanism by...
