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Synthesis of diketal diamines and bis-diketal diamines, cyclams and bicyclams...
Over the last 40 years, much work has been achieved for the conception of macrocycles in order to access to new biologically active compounds. In this context, we... -
Contribution of molecular modeling to the study of human disease : Applicatio...
Pas de résumé en anglais -
First pharmacomodulations of meiogynin A, an inhibitor of the Bcl-xL/Bak inte...
The control of the apoptosis is one of the new modern key to fight against the cancer. The apoptosis is the self destruction of cells, part of the homeostasis, which... -
Influence of additives on the crystallization of active pharmaceutical ingred...
Crystallization from solution is widely used as a separation and purification technique in the pharmaceutical industry. The habit and size of crystal plays a crucial... -
Search for antiplasmodial compounds from the malagasy biodiversity
As part of the search for new compounds with antiplasmodial activity, two malagasy plants were studied: Pyrostria major (Rubiaceae) and Gonioma malagasy (Apocynaceae).... -
STRUCTURE-FUNCTION STUDY OF GLYCOCONJUGATES AND LECTINS
Structural glycobiology is the branch of biology that study the structure and interaction of glycomolecules that play key roles in all living systems The first part of... -
Comprehensive study of Candida antarctica lipase B enantioselectivity : using...
The lipase B from Candida antarctica is an enzyme displaying enantioselective properties which are interesting to obtain enantio pure compounds by kinetic resolution... -
Modeling ion adsorption in carbon nanopores
The capacitance increase observed in nanoporous carbons opens the door for new optimisations of supercapacitors. The purpose of this work is to understand the... -
Etude de complexes de gadolinium d'intérêt pour l'IRM : simulations ab initio...
Currently MRI exams use contrast agents to enhance contrast imaging and so diagnostics. A contrast agent is most of the time a gadolinium complex in which a chelate... -
Exploring the recognition of membrane curvature by the ALPS motif
Some biological processes such as vesicular transport are regulated by motifs that guide proteins to curved membranes. One of them is the ALPS (Amphipathic Lipid... -
Polynitrogen compounds derived from hydrazines : synthesis, characterization ...
High nitrogen content energetic compounds, envisioned as a first step towards High EnergyDensity Materials (HEDM) for space propulsion, were prepared from hydrazine... -
Synthesis and molecular modelling of bio-based polyamides
In the current context of oil resources rarefaction, the development of biobased polymers is of major importance. The present work focused on the development of a... -
Evaluation of chemicals explosive properties: from classical experimental met...
International audience -
Understanding of adsorption mechanism and tribological behaviors of C18 fatty...
The current requirements in automotive lubrication impose complex formulation. Among all the additives present in oil, the presence of molybdenum dithiocarbamate and...
