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B cell development arrest upon insertion of a neo gene between JH and Emu: pr...
Previous targeting experiments within the IgH locus have shown that V(D)J recombination was affected by an insertion of a neo gene within E(mu) upstream of the core... -
Development of a new bicistronic retroviral vector with strong IRES activity.
BACKGROUND: Internal Ribosome Entry Site (IRES)-based bicistronic vectors are important tools in today's cell biology. Among applications, the expression of two... -
No evidence for an association between the -871 T/C promoter polymorphism in ...
Polyclonal B cell activation might be related to pathogenic over-expression of B-cell-activating factor (BAFF) in primary Sj?n's syndrome (pSS) and other autoimmune... -
Characterization of two candidate genes, NCoA3 and IRF8, potentially involved...
BACKGROUND: The persistence of latent HIV-1 reservoirs is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral... -
Designing a HER2/neu promoter to drive alpha1,3galactosyltransferase expressi...
INTRODUCTION: Our goal was to specifically render tumor cells susceptible to natural cytolytic anti-alphaGal antibodies by using a murine alpha1,3galactosyltransferase... -
Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tube...
International audience -
Functional complementation of RNA interference mutants in trypanosomes.
BACKGROUND: In many eukaryotic cells, double-stranded RNA (dsRNA) triggers RNA interference (RNAi), the specific degradation of RNA of homologous sequence. RNAi is now...
