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Study of immune thrombocytopenia pathogenesis
Immune thrombocytopenia (ITP) is an autoimmune disease responsible for a peripheral immune destruction of platelets associated with an inappropriate bone marrow... -
Functional and prognostic aspects of myeloid suppressor cells and Foxp3 in ca...
Evasion of immune surveillance by certain tumour cells seems to be a basic requirement for tumour development in preclinical models and in humans. The mechanisms by... -
CD4+ T cells and regulatory T cell functions in immunotherapy and in the path...
Cerebral accumulation of aggregated Aβ40-42 peptides is among the major pathological hallmarks of Alzheimer's disease (AD). In spite of encouraging results of Aβ... -
Functional and phenotypical alterations of plasmacytoid dendritic cells and r...
Ovarian cancer (OC) is an immunogenic disease and represents a good model for studying antitumoral immunity. We performed a systematic comparison between plasmacytoid... -
Immunoregulatory effects of GILZ (Glucocorticoid-induced leucine zipper) prot...
We previously showed in vitro that DCs with a high level of GILZ activate regulatory T cells (Tregs) whereas DCs with low level of GILZ trigger effector T lymphocytes....
