-
Design of vector for the expression of shRNA in transgenic animals
Small interfering RNAs (siRNAs) are still rarely used in transgenic vertebrates to knockdown gene expression. Indeed, the in vitro highly efficient expression vectors... -
Adenovirus mediated RNA interference as new therapeutic tool against cervical...
Cervical cancer is the third most common female cancer. Infection by human papillomavirus (mainly HPV-16 and 18), with tropisms for mucosal or cutaneous squamous... -
Regulation and retrograde coordination of mitochondrial gene expression
The complex genetic system of higher plant mitochondria could not be studied by transgenic approaches because conventional methods do not permit genetic transformation...
