9 datasets found

Rheumatoid arthritis (RA) is the most frequently autoimmune disease with a prevalence of 1%. Resident cells of joints, the fibroblast-like synoviocytes (FLS), act as...

Chikungunya is an Alphavirus transmitted by mosquitoes (Aedes) and which causes fever, rash, myalgia and arthralgia. The disease (CHIKVD) is transient but severe forms...

Blood platelets are anucleated cells which play a major role on primary hemostasis and well demonstrated other functions in inflammation. Platelets store and secrete a...

Intravesical instillation of bacillus Calmette-Guérin (BCG) for non-muscle invasive bladder cancer is one of the few examples of successful immunotherapy in the...

The prototypic long pentraxin PTX3, a soluble pattern recognition receptor, plays an important role in innate defense against selected pathogens, by favoring their...

The first bacterial strains resistant to antibiotics appeared 70 years ago and have proliferated in recent years causing a serious public health problem. Such bacteria...

Alzheimer’s disease (AD) is characterized by the accumulation of amyloid β (Aβ) in the brain. Several lines of evidences point towards a strong link between AD and...

The rainbow trout (Oncorhynchus mykiss) is one of most significant fish model in many scientific fields, including immunology. Due to its importance in aquaculture,...

The type 1 diabetes ( T1D ) is an autoimmune disease characterized by the destruction of β cells in the pancreas by autoreactive T lymphocytes. During my thesis, we...