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C-H functionalization of purines : synthesis of potential inhibitors of HSP90
Resistance to current treatments of cancer encourages finding new therapeutical targets. The heat shock protein 90 (hsp90) is a molecular chaperon which regulates the... -
Role of heat shock proteins in the regulation of transcription factor HIF
Both HIF1α and HIF2α proteins are highly involved in the development of pathologies, such as cancers, which are prime public health issues. These proteins are...
