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Biochemical, structural and functionnal studies of the histone chaperone / el...
Production of functional messenger RNA (mRNA) requires a complex mechanism that couples transcription with maturation and export of the mRNA. In addition to this... -
Histone post-translational modifications in the nuclei of striatal D1 and D2 ...
The aim of this work is to determine the protein modifications contributing to epigenetic changes in the nuclei of striatal neurons in response to cocaine, and, thus,... -
The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coac...
International audience -
Electrostatic mechanisms involved in the structural plasticity of eukaryotic ...
The local chromatin organization and the processes leading to its dense packing are still puzzling. We aim at understanding the role of local charges and ionic... -
Mechanism of polymerase II transcription repression by the histone variant ma...
macroH2A (mH2A) is an unusual histone variant consisting of a histone H2A-like domain fused to a large nonhistone region. In this work, we show that histone mH2A... -
Nucleolin is a histone chaperone with FACT-like activity and assists remodeli...
International audience -
The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct...
International audience
