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Study of mechanisms involved in the resistance to apoptosis of cells infected...
- Résumé en anglais : Our team is working on the mechanisms of apoptosis induced by nutlin-3, a small molecule which binds to MDM2 and activates p53, in different... -
3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.
International audience -
ER stress inhibits neuronal death by promoting autophagy
Endoplasmic reticulum (ER) stress has been implicated in neurodegenerative diseases but its relationship and role in disease progression remain unclear. Using genetic... -
Endosomal protein sorting and autophagy genes contribute to the regulation of...
Accumulating evidence from various organisms points to a role for autophagy in the regulation of life span. By performing a genome-wide screen to identify novel life... -
DHPR α1S subunit controls skeletal muscle mass and morphogenesis
The α1S subunit has a dual function in skeletal muscle: it forms the L-type Ca2+ channel in T-tubules and is the voltage sensor of excitation-contraction coupling at... -
Role of endoplasmic reticulum stress and autophagy in the regulation of immun...
Under pathological conditions, kidney is subjected to multiple toxic, ischemic and immunological failures that promote the occurrence of chronic kidney disease and the... -
Survival of interneurons and parallel fiber synapses in a cerebellar cortex d...
International audience -
Molecular crosstalk between apoptosis and autophagy induced by a novel 2-meth...
International audience -
Purkinje cell death: Differences between developmental cell death and neurode...
This review is devoted to Purkinje cell death occurring during development and in spontaneous cerebellar mutations of the mouse. We first present evidence in favor of... -
NFκB-dependent autophagy : a response mechanism to hypothermia and protein ag...
The heat shock response is a widely described defense mechanism during which the preferential expression of heat shock proteins (Hsps) helps the cell to recover from... -
The control of selective autophagy and tumor reprogramming through the scaffo...
Despite recent advances, cancer remains the leading cause of death in France with~150,000 annual deaths (INCA, 2012). Notably, lung cancer is one of the most... -
Recent progress in elucidating signalling proteolytic pathways in muscle wast...
Review issu de l'abstract présenté aux 8th International Symposium on Amino Acid and Protein Metabolism in Health and Disease -
BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protei...
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Morphogenesis of membranar compartments : autophagosome formation in plants
Autophagy is a catabolic process targeting cytosolic compounds to the lytic compartment after sequestration within a double membrane bound vesicle: the autophagosome.... -
Antiestrogen-binding site ligands induce autophagy in myeloma cells that proc...
International audience
