11 datasets found

Skeletal muscle cells are composed of contractile elements wrapped in a membrane network. Formation and maintenance of skeletal muscle involve muscle precursor...

The characterization of the interactions of different biomolecules such as proteins and peptides with lipids, constitute a crucial step for better understanding the...

Background and Aim: TRAIL has sparked a growing interest in oncology due to its ability to selectively trigger cancer cell death while sparing normal cells. The...

CDKN1A gene was initially identified as a target of the tumor suppressor p53. The ability to inhibitcyclin-dependant kinase and PCNA activities confers to its product,...

Cadherins are intercellular adhesion receptors allowing to make a link between the adjacent cell and the cytoskeleton. During cell contact formation, cadherins...

We study the influence of the VASP protein on dynamics and mechanics of the actin networks that drive cell motility. Our experimental setup is an in vitro bead system...

Covering the apex of intestinal cells, microvilli are microscopic membrane protrusions structured by a network of actin filaments organized by actin binding proteins....

Actin filaments play a fundamental role in cell mechanics: assembled into networks by a large number of partners, they ensure cell integrity, deformability, and...

The cytoskeleton is a composite and versatile structure that confers complex mechanical properties to the cells. In particular the actin cytoskeleton dynamically...

We studied the growth of asymmetric cellular contacts : adherens junctions and focal contacts. We showed, by imaging, micromanipulation and cellular assembly...

Bone remodeling is a physiological process by which old bone is replaced by new bone. Osteoclasts are multinucleated giant cells of the monocytic lineage. Their...