-
In vivo evolution of a beta-lactamase like activity throughout idiotypic pathway
An abzyme (9G4H9) displaying a -lactamase activity was obtained through the idiotypic pathway and has been previously described. Analysis of the catalytic mechanism by... -
Idiotypic network mimicry and antibody catalysis: lessons for the elicitation...
An important challenge in the field of catalytic antibodies is the generation of antibodies with designed sequence-specific protease activities. Such catalysts would...
