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Effects of red wine polyphenols on cell proliferation and resveratrol metabolism
It is known that moderate consumption of red wine may protect against many diseases, in particular because of its polyphenols. We studied in particular the effect of... -
Chloroacetaldehyde : from the implication in the pathophysiological mechanism...
Chloroacetaldehyde (CAA), one of the main products of ifosfamide (IFO) hepatic metabolism, is considered as responsible of IFO nephrotoxicity. The mechanisms of this... -
Chromatin assembly factors and heterochromatin organization during cell proli...
In cancer cells, the organization of DNA in chromatin is frequently affected. Thus, it is crucial to understand how factors involved in chromatin organization... -
Hyperproliferative Phenotype of Deep Infiltrating Endometriosis Cells
Endometriosis, a common disease that affects approximately 8 to 10% of women of childbearing age, is responsible for chronic pelvic pain and infertility. There is... -
Study of the SnAK/SnRK1 ("SnRK1‐Activating Kinase/SNF1‐Related Kinase 1") sig...
The conserved family of protein kinases SNF1/AMPK/SnRK1 (yeast/mammals/plants) is considered as a central element of cell metabolism regulation by controlling both... -
Functional study of smap1 : a new gene linking vesicular traffic and oncogenesis
Tumours that are deficient in mismatch repair system accumulate numerous mutations throughout the genome in repeated sequences, called microsatellites. Genes that...
