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Causes and consequences of type I IFN activation in autoimmune diseases. Stud...
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease (AID) that presents similar characteristics to systemic lupus erythematosus. These characteristics... -
Kinetics of DNA methylation inheritance by the Dnmt1-including complexes duri...
International audience -
Flyway evolution is too fast to be explained by the modern synthesis: proposa...
International audience -
Natural single-nucleosome epi-polymorphisms in yeast.
International audience -
H3S10P, Phosphorylation at Ser10 in Mouse Preimplantation Embryos
Pericentromeric heterochromatin appears to be involved with gene regulation and therefore with the developmental potential of embryos. We hypothesized that an... -
Biochemical, structural and functionnal studies of the histone chaperone / el...
Production of functional messenger RNA (mRNA) requires a complex mechanism that couples transcription with maturation and export of the mRNA. In addition to this... -
The Methyl-CpG Binding Domain protein 2 (MBD2), a DNA methylation-dependent t...
The Methyl-CpG-Binding Domain (MBD) proteins represent key molecules in the interpretation ofDNA methylation signals leading to gene silencing through recruitment of... -
Assisted reproductive technologies and quality of gametes and embryos : evalu...
Assisted reproductive technologies particularly the induction of ovulation, oocytes in vitro maturation, and prolonged embryo culture require in vitro manipulation of... -
Specific inhibition of one DNMT1-including complex influences tumor initiatio...
International audience -
Functional characterization of the histone acetyltransferase GCN5 in the huma...
In order to initiate the transcription by the RNA polymerase II, chromatin needs to be modified by coactivators. Some of these coactivators are histone... -
Modulation of estrogen receptor alpha activity and expression during breast c...
International audience -
Study of the impact of microARNs on the carcinogenèse of cancers unstable col...
MSI tumor progression (Microsatellite Instability) is depicted as a multistage process that results from mutations generated by a process of genetic instability...
