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Interactions outside the boundaries of the canonical binding groove of a PDZ ...
The postsynaptic density protein-95/discs large/zonula occludens-1 (PDZ) domain is a protein-protein interaction module with a shallow binding groove where protein... -
Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficki...
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Congenital hypothyroidism mutations affect common folding and trafficking in ...
The α/β-hydrolase fold superfamily of proteins is composed of structurally related members that, despite great diversity in their catalytic, recognition, adhesion and... -
Functional evidence that a recently evolved Drosophila sperm-specific gene bo...
In many species, both morphological and molecular traits related to sex and reproduction evolve faster in males than in females. Ultimately, rapid male evolution... -
Structural and functional characterization of Schistosoma mansoni Thioredoxin.
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Fluoride as a probe for H-bonding interactions in the active site of heme pro...
The structural and functional properties of the active site of the bacterial hemoglobin from Thermobifida fusca are largely determined by three polar amino acids:... -
mRNA stability and control of cell proliferation.
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The optical spectra of fluoride complexes can effectively probe H-bonding int...
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Stenotrophomonas maltophilia strains from cystic fibrosis patients: genomic v...
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Open conformation of human DOPA decarboxylase reveals the mechanism of PLP ad...
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The superoxide reductase from the early diverging eukaryote Giardia intestina...
Unlike superoxide dismutases (SODs), superoxide reductases (SORs) eliminate superoxide anion (O(2)(*-)) not through its dismutation, but via reduction to hydrogen... -
Giardia intestinalis escapes oxidative stress by colonizing the small intesti...
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Influence of previous tuberculin skin test on serial IFN-γ release assays.
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miRNAs as serum biomarkers for Duchenne muscular dystrophy.
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Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation ...
Increased expression or aberrant activation of c-Myc plays an important role in leukemogenesis. Here, we show that in acute myeloid leukemia (AML), c-Myc directly... -
In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviro...
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miR-31 modulates dystrophin expression: new implications for Duchenne muscula...
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Identification of small-molecule inhibitors of the XendoU endoribonucleases f...
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Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to ...
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A subset of chronic lymphocytic leukemia patients display reduced levels of P...
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease characterized by defects in the DNA damage response and apoptosis. Among the factors involved in these...
